Three other people have also been taken to hospital.
Gardaí in Tullamore, Offaly are investigating a fatal road traffic collision which occurred at Scrubb, Killeigh at approximately 17:00 on Monday, 27 May.
A car and an articulated truck were involved in the collision.
The male driver of the car and his passenger, a five-year-old boy, have died.
Two other passengers in the car required medical assistance and have been taken to hospital.
A young girl has been airlifted to Crumlin Children’s Hospital with life threatening injuries, while another male passenger has been taken to Midland Regional Hospital in Tullamore.
The man driving the truck has also been taken to the Midland Regional Hospital in Tullamore with minor injuries.
The road is currently closed to facilitate a Garda forensic collision examination and local diversions are in place.
Gardaí are appealing for anyone with information in relation to this collision to contact Tullamore Garda Station on 057-9327600, the Garda Confidential Line 1800 666 111 or any Garda Station.
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